LSKB Bio Knowledge Provide a Variety of Search Functions

Basic Searches

• Search for genes using accession or ID, GO, microarray probe searches and the batch search using the lists of genes, probes, and PMIDs.
• Analyze ontology functions (GO), disease, and compounds using gene lists.
• Advanced Search; Analysis of GO terms from a list of genes

Batch searches

Variety of batch search is available, such as “from Gene ID or Genome location”, “Microarray probe”, “PMID”, “mRNA “, “PDBID”, and more.

PharmacoGenomics

• Use keywords to obtain various compounds
• Use genes to survey proteins, domains, and 3D structural information.
• Survey genes linked to PDB 3D structures or Bioassay
• Search for proteins based on their molecular mass
• Search for proteins that are drug targets
• Please refer to "Chem Knowledge" for extended information based on chemical structures

Bayes analysis tool

Bayes based data analysis such as a machine learning method is important calculate probability score by objectively. LSKB prepare pre-installed the “GSEA based curated drug response learning data set” from GEO data, and be able to calculate similarity score for drug or experiment by expression pattern. To optimizing learning dataset, WF recommend creating own your dataset and import , management and analysis in LSKB.

GEO data analysis and Knowledge from GEO

The system includes important gene sets from selected more than 100 disease based deferential express and statistical analysis results from GEO data. This can be use good reference of your expression or NGS data. The selected GEO data sets realized experiment based GSEA analysis, which are generated up-regulated or down-regulated gene sets for each study by human curated data are objectively find similar experiment from GEO data. The data set will be update by world fusion scientists, that will be distribute through our download web site.