
World Fusion provides analysis and exploration services using innovative software and AI.
World Fusion Co., Ltd. provides contract research and software services for drug discovery and microbiome research. The contract research business provides a service specializing in bioinformatics to search for target proteins from diseases and compounds. Microbiome's services include metagenomic analysis, advanced microbial community analysis, and microbial function exploration. These services use a variety of software, and the software is also available for use
Services
Services
The service is available to anyone, so biotech companies and academic researchers are welcome to contact us.
Microbiome Contract Research Services
Over a decade of proven experience in oral, skin, and gut microbiome analysis
We provide full-service microbiome analysis tailored to your research or product development goals.
Analyze from DNA or fastq files

Microbiome Seed Discovery Services
Find your next lead compound — from the microbiome
Our platform leverages in-house databases and proprietary analytics to discover functional bioactives and seed compounds.
From Skin, Oral, Gut microbiota

Target/biomarker discovery service
We utilize large-scale, comprehensive biological data and AI, bioinformatics, and chemoinformatics methods to provide services for discovering targets and biomarkers from diseases, and for discovering compounds and candidate therapeutic drugs from biomarkers.

In-silico prediction of
phenotype screening data
Phenotype Screening Service predicts phenotypes from gene expression data of model animals using phenotypic assay data such as drug responsiveness and developmental toxicity in model animals.
We also support the creation of gene sets tailored to specific purposes and the creation of orthologous genes in model animals.

Background Software and Technologies
Target Discovery pipeline
We use over 60 databases and process pipeline necessary for target discovery and have adjusted them to be optimal for target discovery and drug repurposing.
The database and pipeline supports humans, mice, rats, and zebrafish, and can be used for predicting toxicity from phenotype screening. It also includes the results of literature analysis, allowing you to obtain the functions between diseases and targets reported in the literature, as well as the relationships between biomarkers, targets, toxicity, etc.

Metagenomic analysis pipeline
Metagenomic analysis pipeline is an important technique for visualizing the state and effects of various environments. Based on the technology we have acquired through our contract research services specializing in the environment, medicine, food, and cosmetics, we have developed and using various software and databases, including basic metagenomic analysis, whole genome metagenomic analysis, statistical analysis specialized for microbial communities, and functional analysis.

Literature Analysis Powered by Ontology & AI
Literature analysis is required at various stages. By using the vast ontology dictionary terms, text mining and MNLI techniques, we have developed a database that can be used for target and biomarker discovery, toxicity evaluation, and more broadly, functional analysis of microorganisms.

Microbiome Expert AI engine
A domain-specialized LLM chatbot tailored for microbiome science.
Microbiome Expert AI is an intelligent chatbot built on LLaMA 3.2 and fine-tuned for deep scientific reasoning in microbiology and infectious disease domains.

Software for Deliver
Metagenomic Analysis Software
Metagenome@KIN
Intuitive 16S/ITS metagenomic analysis software
Metagenome@KIN is a user-friendly desktop tool for analyzing next-generation sequencing data based on 16S rRNA and ITS.
WHMetagenome@KIN
WHMetagenome@KIN is a Windows-based tool for analyzing whole metagenome shotgun sequencing data from Illumina platforms.
@KIN Web Stat
Web-based platform for performing advanced statistical analyses on microbiome data, with an intuitive interface suited for researchers of all backgrounds.
Available features include:
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Kruskal–Wallis test for α-diversity analysis
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PERMANOVA for β-diversity comparisons
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LEfSe for biomarker discovery
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PICRUSt2 for predictive functional profiling
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Microbiome Expert AI — a domain-specialized LLM chatbot for literature-based insights

Literature Similarity Search & Management Platform
LiBLA(Scientific Literature Lookup Assistant system for PubMed) is a tool designed to assist users find articles of interest more objectively by analyzing commonalities in the abstracts of registered articles.
LiBLA objectively replaces the need for you to manually review papers, find commonalities, and perform repeated PubMed searches, generating weekly recommendations.
